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Negotiating the Relationship Between Addiction, Ethics, and Brain Science PMC

These environmental factors critically include availability of drugs, but also of healthy alternative rewards and opportunities. As we will show, stating that brain mechanisms are critical for understanding and treating addiction in no way negates the role of psychological, social and socioeconomic processes as both causes and consequences of substance use. To reflect this complex nature of addiction, we have assembled a team with expertise that spans from molecular neuroscience, through animal models of addiction, human brain imaging, clinical addiction medicine, to epidemiology. What brings us together is a passionate commitment to improving the lives of people with substance use problems through science and science-based treatments, with empirical evidence as the guiding principle. Metacontingencies represent an important approach to addiction because their behavior analytic origins emphasize the role of functional relationships that determine behavior. Unlike other approaches that consider personal factors as imbedded within and inseparable from the social context (e.g., relational autonomy), metacontingencies recognize the separateness yet interdependence of these factors.

These factors may indicate a certain level of group risk for problematic substance use, but cannot verify either the likelihood of substance use occurring within the group or which individuals within the group are more likely to be affected. These factors are not inherent in the composition of the social structure, are neither stable nor persistent, but are governed by the social values and norms of that social system or group (Bunge 2003). In the 25 years that have elapsed since Engel first proposed http://blogstyle.ru/inform/31 the biopsychosocial model, two new intellectual trends have emerged that could make it even more robust. First, we can move beyond the problematic issue of mind-body duality by recognizing that knowledge is socially constructed. They are useful to the extent that they focus our thinking and action in helpful ways (eg, they contribute to health, well-being, and efficient use of resources), but when taken too literally, they can also entrap and limit us by creating boundaries that need not exist.

Drug Addiction is a Major Problem

Three received opioid maintenance therapy (OMT) and were in contact with a GP or therapist. Eight had been in treatment for trauma, anxiety, depression, psychosis or insomnia, and three had or were waiting for treatment for ADHD. Also, four informants https://oval.ru/ars/083079084.html mentioned participation in activities and support groups run by NGOs, as described above. Five informants had received inpatient treatment for substance use and mental health problems or detox several times since they left Tyrili.

The social burden of illicit drug addiction is estimated at billions of dollars per year (Fisher, Oviedo-Joekes, Blanken, et al. 2007). Research that involves providing drugs to individuals living with an addiction must negotiate between science, ethics, politics, law, and evidence-based medicine. For instance, despite its cost-effectiveness and ease on burden of disease, the supervised injection site (SIS) in the Downtown Eastside area of Vancouver, Canada has been repeatedly threatened with closure by politicians. The threats are based https://www.rajasthan-northindia-tours.com/hotels-in-rajasthan/hotels-in-bharatpur/the-bagh-heritage-hotel-in-bharatpur.html on emotional and moral attitudes towards the existence of the SIS and drug addicts generally, as opposed to empirical evidence (Des Jarlais, Arasteh, and Hagan 2008). Notions of a pathologized self, deeply enmeshed with personal identity, may lead an individual to internally negotiate a relationship between the self and the brain (Dumit 2003). It may further challenge understandings of “accepted” identities, such as health seeking and rational, as opposed to “contested” identities, such as addict, intoxicated, and at-risk (Fry 2008).

Theories and Biological Basis of Addiction

The authors outlined an agenda closely related to that put forward by Leshner, but with a more clinical focus. Their conclusion was that addiction should be insured, treated, and evaluated like other diseases. This paper, too, has been exceptionally influential by academic standards, as witnessed by its ~3000 citations to date. What may be less appreciated among scientists is that its impact in the real world of addiction treatment has remained more limited, with large numbers of patients still not receiving evidence-based treatments. For instance, medications designed specifically for substance use disorders target the central nervous system in ways to minimize the effectiveness of the addictive substance (e.g., buprenorphine/naloxone for opioid use disorder). Other medications impact the nervous system to decrease the influence of comorbid psychiatric conditions that drive addictive behavior (e.g., antidepressants, anxiolytics).

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